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Fibrin Accumulation Secondary to Loss of Plasmin-Mediated Fibrinolysis Drives Inflammatory Osteoporosis in Mice

OBJECTIVE: Osteoporosis is a skeletal disorder characterized by low bone mass and increased bone fragility associated with aging, menopause, smoking, obesity, or diabetes. Persistent inflammation has been identified as an instigating factor in progressive bone loss. In addition to the role of fibrin...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Cole, Heather A., Ohba, Tetsuro, Nyman, Jeffry S., Hirotaka, Haro, Cates, Justin M. M., Flick, Matthew J., Degen, Jay L., Schoenecker, Jonathan G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474376/
https://ncbi.nlm.nih.gov/pubmed/24664548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38639
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