Fibrin Accumulation Secondary to Loss of Plasmin-Mediated Fibrinolysis Drives Inflammatory Osteoporosis in Mice

OBJECTIVE: Osteoporosis is a skeletal disorder characterized by low bone mass and increased bone fragility associated with aging, menopause, smoking, obesity, or diabetes. Persistent inflammation has been identified as an instigating factor in progressive bone loss. In addition to the role of fibrin...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Cole, Heather A., Ohba, Tetsuro, Nyman, Jeffry S., Hirotaka, Haro, Cates, Justin M. M., Flick, Matthew J., Degen, Jay L., Schoenecker, Jonathan G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474376/
https://ncbi.nlm.nih.gov/pubmed/24664548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38639
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