Activated thrombin-activatable fibrinolysis inhibitor (TAFIa) attenuates fibrin-dependent plasmin generation on thrombin-activated platelets

BACKGROUND: Thrombin-activated platelets can promote fibrinolysis by binding plasminogen in a fibrinogen-dependent manner and enhancing its activation by tissue-type plasminogen activator (t-PA). Whether t-PA also binds to activated platelets and the mechanism for regulation of platelet-dependent fi...

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Publicado en:J Thromb Haemost
Autores principales: Ni, Ran, Neves, Miguel A. D., Wu, Chengliang, Cerroni, Samantha E., Flick, Matthew J., Ni, Heyu, Weitz, Jeffrey I., Gross, Peter L., Kim, Paul Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7719609/
https://ncbi.nlm.nih.gov/pubmed/32506822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14950
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