Isolation, Co-Crystallization and Structure-Based Characterization of Anabaenopeptins as Highly Potent Inhibitors of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFIa)

Mature thrombin activatable fibrinolysis inhibitor (TAFIa) is a carboxypeptidase that stabilizes fibrin clots by removing C-terminal arginines and lysines from partially degraded fibrin. Inhibition of TAFIa stimulates the degradation of fibrin clots and may help to prevent thrombosis. Applying a lea...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Sci Rep
المؤلفون الرئيسيون: Schreuder, Herman, Liesum, Alexander, Lönze, Petra, Stump, Heike, Hoffmann, Holger, Schiell, Matthias, Kurz, Michael, Toti, Luigi, Bauer, Armin, Kallus, Christopher, Klemke-Jahn, Christine, Czech, Jörg, Kramer, Dan, Enke, Heike, Niedermeyer, Timo H. J., Morrison, Vincent, Kumar, Vasant, Brönstrup, Mark
التنسيق: Artigo
اللغة:Inglês
منشور في: Nature Publishing Group 2016
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5015106/
https://ncbi.nlm.nih.gov/pubmed/27604544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep32958
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة