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Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence

Salmonella PhoQ is a histidine kinase with a periplasmic sensor domain (PD) that promotes virulence by detecting the macrophage phagosome. PhoQ activity is repressed by divalent cations and induced in environments of acidic pH, limited divalent cations, and cationic antimicrobial peptides (CAMP). Pr...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Hicks, Kevin G, Delbecq, Scott P, Sancho-Vaello, Enea, Blanc, Marie-Pierre, Dove, Katja K, Prost, Lynne R, Daley, Margaret E, Zeth, Kornelius, Klevit, Rachel E, Miller, Samuel I
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473727/
https://ncbi.nlm.nih.gov/pubmed/26002083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06792
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