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The PhoQ Histidine Kinases of Salmonella and Pseudomonas spp. are Structurally and Functionally Different: Evidence that pH and Antimicrobial Peptide Sensing Contribute to Mammalian Pathogenesis

The PhoQ sensor-kinase is essential for Salmonella typhimurium virulence for animals, and a homolog exists in the environmental organism and opportunistic pathogen Pseudomonas aeruginosa. S. typhimurium PhoQ (ST-PhoQ) is repressed by millimolar concentrations of divalent cations and activated by ant...

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Dettagli Bibliografici
Autori principali: Prost, Lynne R., Daley, Margaret E., Bader, Martin W., Klevit, Rachel E., Miller, Samuel I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555970/
https://ncbi.nlm.nih.gov/pubmed/18532985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06303.x
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