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Osteopontin inhibits HIF-2α mRNA expression in osteoarthritic chondrocytes

The aim of the present study was to investigate the in vitro effect of osteopontin (OPN) on the expression of hypoxia-inducible factor-2α (HIF-2α) in chondrocytes and the role of OPN in osteoarthritis (OA). Cartilage was purified from the tibial surfaces of patients with OA of the knee and cultured...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: CHENG, CHAO, ZHANG, FANG-JIE, TIAN, JIAN, TU, MIN, XIONG, YI-LIN, LUO, WEI, LI, YU-SHENG, SONG, BING-BING, GAO, SHU-GUANG, LEI, GUANG-HUA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473661/
https://ncbi.nlm.nih.gov/pubmed/26136997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2434
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