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Effect of osteopontin on the mRNA expression of ADAMTS4 and ADAMTS5 in chondrocytes from patients with knee osteoarthritis

Previous studies have demonstrated that osteopontin (OPN) levels are elevated in the synovial fluid and articular cartilage, and are associated with the severity of knee osteoarthritis (OA). However, the role of OPN in the pathogenesis of OA has yet to be elucidated. The present study aimed to inves...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: GAO, SHU-GUANG, ZENG, CHAO, SONG, YANG, TIAN, JIAN, CHENG, CHAO, YANG, TUO, LI, HUI, ZHANG, FANG-JIE, LEI, GUANG-HUA
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471803/
https://ncbi.nlm.nih.gov/pubmed/26136925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2310
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