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The β-catenin/TCF-4 pathway regulates the expression of OPN in human osteoarthritic chondrocytes
BACKGROUND: Cartilage destruction is the main characteristic of osteoarthritis (OA), and osteopontin (OPN) is elevated in OA articular cartilage; however, the reason for the increased OPN level is not determined. In addition, Wnt/β-catenin signaling participates in the progression of OA. The aim of...
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| Publicado no: | J Orthop Surg Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7441722/ https://ncbi.nlm.nih.gov/pubmed/32819387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-020-01881-6 |
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