Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis

Glucocorticoids (GC) are widely used in rheumatoid arthritis (RA). Ongoing active disease due to GC resistance may unfavorably influence long-term disease outcome in RA. We studied the association between the presence of glucocorticoid receptor (GR) and glucocorticoid-induced transcript 1 (GLCCI1) g...

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Detalhes bibliográficos
Publicado no:Rheumatol Int
Main Authors: Quax, R. A. M., Koper, J. W., Huisman, A. M., Weel, A., Hazes, J. M. W., Lamberts, S. W. J., Feelders, R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Original Article - Genes and Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473091/
https://ncbi.nlm.nih.gov/pubmed/25724472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00296-015-3235-z
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