Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis

INTRODUCTION: The glucocorticoid receptor (GR) plays an important regulatory role in the immune system. Four polymorphisms in the GR gene are associated with differences in glucocorticoid (GC) sensitivity; the minor alleles of the polymorphisms N363 S and BclI are associated with relative hypersensi...

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Main Authors: van Oosten, Manon JM, Dolhain, Radboud JEM, Koper, Jan W, van Rossum, Elisabeth FC, Emonts, Marieke, Han, Khik H, Wouters, Jacques MGW, Hazes, Johanne MW, Lamberts, Steven WJ, Feelders, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945062/
https://ncbi.nlm.nih.gov/pubmed/20727199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3118
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