Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation

In Alzheimer’s disease (AD), one of the early responses to Aβ amyloidosis is recruitment of microglia to areas of new plaque. Microglial receptors such as cannabinoid receptor 2 (CB2) might be a suitable target for development of PET radiotracers that could serve as imaging biomarkers of Aβ-induced...

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Vydáno v:PLoS One
Hlavní autoři: Savonenko, Alena V., Melnikova, Tatiana, Wang, Yuchuan, Ravert, Hayden, Gao, Yongjun, Koppel, Jeremy, Lee, Deidre, Pletnikova, Olga, Cho, Eugenia, Sayyida, Nuzhat, Hiatt, Andrew, Troncoso, Juan, Davies, Peter, Dannals, Robert F., Pomper, Martin G., Horti, Andrew G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472959/
https://ncbi.nlm.nih.gov/pubmed/26086915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129618
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