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Synthesis and Pharmacology of Halogenated δ-Opioid-Selective [D-Ala(2)]Deltorphin II Peptide Analogues
Deltorphins are naturally occurring peptides produced by the skin of the giant monkey frog (Phyllomedusa bicolor). They are δ-opioid receptor-selective agonists. Herein, we report the design and synthesis of a peptide, Tyr-D-Ala-(pI)Phe-Glu-Ile-Ile-Gly-NH(2) 3 (GATE3-8), based on the [D-Ala(2)]delto...
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| Gepubliceerd in: | ACS Chem Neurosci |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472604/ https://ncbi.nlm.nih.gov/pubmed/25844930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00060 |
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