Synthesis and Pharmacology of Halogenated δ-Opioid-Selective [D-Ala(2)]Deltorphin II Peptide Analogues

Deltorphins are naturally occurring peptides produced by the skin of the giant monkey frog (Phyllomedusa bicolor). They are δ-opioid receptor-selective agonists. Herein, we report the design and synthesis of a peptide, Tyr-D-Ala-(pI)Phe-Glu-Ile-Ile-Gly-NH(2) 3 (GATE3-8), based on the [D-Ala(2)]delto...

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Xehetasun bibliografikoak
Argitaratua izan da:ACS Chem Neurosci
Egile Nagusiak: Pescatore, Robyn, Marrone, Gina F., Sedberry, Seth, Vinton, Daniel, Finkelstein, Netanel, Katlowitz, Yitzchak E., Pasternak, Gavril W., Wilson, Krista R., Majumdar, Susruta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472604/
https://ncbi.nlm.nih.gov/pubmed/25844930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00060
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