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ADAMTS9 mediated extracellular matrix dynamics regulates umbilical cord vascular smooth muscle differentiation and rotation

Despite the significance for fetal nourishment in mammals, mechanisms of umbilical cord vascular growth remain poorly understood. Here, the secreted metalloprotease ADAMTS9 is shown to be necessary for murine umbilical cord vascular development. Restricting it to the cell-surface using a gene trap a...

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Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Nandadasa, Sumeda, Nelson, Courtney M., Apte, Suneel S.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472575/
https://ncbi.nlm.nih.gov/pubmed/26027930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.005
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