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ADAMTS9 mediated extracellular matrix dynamics regulates umbilical cord vascular smooth muscle differentiation and rotation

Despite the significance for fetal nourishment in mammals, mechanisms of umbilical cord vascular growth remain poorly understood. Here, the secreted metalloprotease ADAMTS9 is shown to be necessary for murine umbilical cord vascular development. Restricting it to the cell-surface using a gene trap a...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Nandadasa, Sumeda, Nelson, Courtney M., Apte, Suneel S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472575/
https://ncbi.nlm.nih.gov/pubmed/26027930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.005
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