Non-toxic antimicrobials that evade drug resistance

Drugs that act more promiscuously provide fewer routes for the emergence of resistant mutants. But this benefit often comes at the cost of serious off-target and dose-limiting toxicities. The classic example is the antifungal amphotericin B (AmB), which has evaded resistance for more than half a cen...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Davis, Stephen A., Vincent, Benjamin M., Endo, Matthew M., Whitesell, Luke, Marchillo, Karen, Andes, David R., Lindquist, Susan, Burke, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472574/
https://ncbi.nlm.nih.gov/pubmed/26030729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1821
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