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Novel Familial Dilated Cardiomyopathy Mutation in MYL2 Affects the Structure and Function of Myosin Regulatory Light Chain

Dilated Cardiomyopathy (DCM) is a disease of the myocardium characterized by left ventricular dilatation and diminished contractile function. In this report we describe a novel DCM mutation identified for the first time in the myosin regulatory light chain (RLC), replacing Aspartic Acid at position...

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Detalhes bibliográficos
Publicado no:FEBS J
Main Authors: Huang, Wenrui, Liang, Jingsheng, Yuan, Chen-Ching, Kazmierczak, Katarzyna, Zhou, Zhiqun, Morales, Ana, McBride, Kim L., Fitzgerald-Butt, Sara M., Hershberger, Ray E., Szczesna-Cordary, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472530/
https://ncbi.nlm.nih.gov/pubmed/25825243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13286
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