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A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method

UC781, a very potent HIV-1 non-nucleoside reverse transcriptase inhibitor with extreme hydrophobicity and poor water solubility, is under development as a topical vaginal microbicide product to prevent HIV transmission. In this study, the thermodynamic behavior of the interaction between UC781 with...

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Bibliografske podrobnosti
izdano v:J Incl Phenom Macrocycl Chem
Main Authors: Yang, Haitao, Parniak, Michael A., Hillier, Sharon L., Rohan, Lisa C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472443/
https://ncbi.nlm.nih.gov/pubmed/26097403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10847-011-0019-2
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