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L-Citrulline increases hepatic sensitivity to insulin by reducing the phosphorylation of serine 1101 in insulin receptor substrate-1

BACKGROUND: Insulin resistance is characterized by deficient responses to insulin in its target tissues. In the present study, we examined the effects of L-Citrulline (L-Cit) on insulin sensitivity and signaling cascades in rat hepatoma H4IIE cells and SHRSP.Z-Leprfa/IzmDmcr rats. METHODS: H4IIE cel...

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Detalhes bibliográficos
Publicado no:BMC Complement Altern Med
Main Authors: Yoshitomi, Hisae, Momoo, Maki, Ma, Xiao, Huang, Yewei, Suguro, Shiori, Yamagishi, Yoshie, Gao, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472399/
https://ncbi.nlm.nih.gov/pubmed/26084330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-015-0706-4
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