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Structural differences of amyloid-β fibrils revealed by antibodies from phage display
BACKGROUND: Beside neurofibrillary tangles, amyloid plaques are the major histological hallmarks of Alzheimer’s disease (AD) being composed of aggregated fibrils of β-amyloid (Aβ). During the underlying fibrillogenic pathway, starting from a surplus of soluble Aβ and leading to mature fibrils, multi...
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| Veröffentlicht in: | BMC Biotechnol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472244/ https://ncbi.nlm.nih.gov/pubmed/26084577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-015-0146-8 |
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