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The influence of antibody fragment format on phage display based affinity maturation of IgG
Today, most approved therapeutic antibodies are provided as immunoglobulin G (IgG), whereas small recombinant antibody formats are required for in vitro antibody generation and engineering during drug development. Particularly, single chain (sc) antibody fragments like scFv or scFab are well suited...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Landes Bioscience
2014
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929444/ https://ncbi.nlm.nih.gov/pubmed/24262918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27227 |
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