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The influence of antibody fragment format on phage display based affinity maturation of IgG

Today, most approved therapeutic antibodies are provided as immunoglobulin G (IgG), whereas small recombinant antibody formats are required for in vitro antibody generation and engineering during drug development. Particularly, single chain (sc) antibody fragments like scFv or scFab are well suited...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Steinwand, Miriam, Droste, Patrick, Frenzel, Andrè, Hust, Michael, Dübel, Stefan, Schirrmann, Thomas
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Landes Bioscience 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929444/
https://ncbi.nlm.nih.gov/pubmed/24262918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27227
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