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The influence of antibody fragment format on phage display based affinity maturation of IgG
Today, most approved therapeutic antibodies are provided as immunoglobulin G (IgG), whereas small recombinant antibody formats are required for in vitro antibody generation and engineering during drug development. Particularly, single chain (sc) antibody fragments like scFv or scFab are well suited...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3929444/ https://ncbi.nlm.nih.gov/pubmed/24262918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27227 |
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