Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model

Osteoarthritis (OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study it...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bone Res
Main Authors: Zhang, Xianrong, Zhu, Ji, Liu, Fei, Li, Yumei, Chandra, Abhishek, Levin, L Scott, Beier, Frank, Enomoto-Iwamoto, Motomi, Qin, Ling
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472123/
https://ncbi.nlm.nih.gov/pubmed/26120493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.15
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