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Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model
Osteoarthritis (OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study it...
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Udgivet i: | Bone Res |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Nature Publishing Group
2014
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4472123/ https://ncbi.nlm.nih.gov/pubmed/26120493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2014.15 |
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