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Autocrine and Paracrine Actions of IGF-I Signaling in Skeletal Development

Insulin-like growth factor-I (IGF-I) regulates cell growth, survival, and differentiation by acting on the IGF-I receptor, (IGF-IR)-a tyrosine kinase receptor, which elicits diverse intracellular signaling responses. All skeletal cells express IGF-I and IGF-IR. Recent studies using tissue/cell-speci...

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Publicado en:Bone Res
Autores principales: Wang, Yongmei, Bikle, Daniel D., Chang, Wenhan
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472106/
https://ncbi.nlm.nih.gov/pubmed/26273506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4248/BR201303003
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