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Block of postjunctional muscle-type acetylcholine receptors in vivo causes train-of-four fade in mice

BACKGROUND: Train-of-four (TOF) fade during nerve-mediated muscle contraction is postulated to be attributable to inhibition of prejunctional nicotinic α3β2 acetylcholine receptors (nAChRs), while decrease of twitch tension is attributable to block of postjunctional muscle nAChRs. The validity of th...

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Detalhes bibliográficos
Publicado no:Br J Anaesth
Main Authors: Nagashima, M., Sasakawa, T., Schaller, S. J., Martyn, J. A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471818/
https://ncbi.nlm.nih.gov/pubmed/25835024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aev037
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