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Mechanism of Tacrine Block at Adult Human Muscle Nicotinic Acetylcholine Receptors
We used single-channel kinetic analysis to study the inhibitory effects of tacrine on human adult nicotinic receptors (nAChRs) transiently expressed in HEK 293 cells. Single channel recording from cell-attached patches revealed concentration- and voltage-dependent decreases in mean channel open prob...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229521/ https://ncbi.nlm.nih.gov/pubmed/12198092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028583 |
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