Riluzole blocks human muscle acetylcholine receptors

Riluzole, the only drug available against amyotrophic lateral sclerosis (ALS), has recently been shown to block muscle ACh receptors (AChRs), raising concerns about possible negative side-effects on neuromuscular transmission in treated patients. In this work we studied riluzole's impact on the...

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Detalhes bibliográficos
Main Authors: Deflorio, Cristina, Palma, Eleonora, Conti, Luca, Roseti, Cristina, Manteca, Alessia, Giacomelli, Elena, Catalano, Myriam, Limatola, Cristina, Inghilleri, Maurizio, Grassi, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Neuroscience: Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424768/
https://ncbi.nlm.nih.gov/pubmed/22431338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.230201
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