Physiological characterization of human muscle acetylcholine receptors from ALS patients

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motor neurons leading to muscle paralysis. Research in transgenic mice suggests that the muscle actively contributes to the disease onset, but such studies are difficult to pursue in humans and in vitro models would...

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Main Authors: Palma, Eleonora, Inghilleri, Maurizio, Conti, Luca, Deflorio, Cristina, Frasca, Vittorio, Manteca, Alessia, Pichiorri, Floriana, Roseti, Cristina, Torchia, Gregorio, Limatola, Cristina, Grassi, Francesca, Miledi, Ricardo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250127/
https://ncbi.nlm.nih.gov/pubmed/22128328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117975108
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