Physiological characterization of human muscle acetylcholine receptors from ALS patients

Amyotrophic lateral sclerosis (ALS) is characterized by progressive degeneration of motor neurons leading to muscle paralysis. Research in transgenic mice suggests that the muscle actively contributes to the disease onset, but such studies are difficult to pursue in humans and in vitro models would...

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Detaylı Bibliyografya
Asıl Yazarlar: Palma, Eleonora, Inghilleri, Maurizio, Conti, Luca, Deflorio, Cristina, Frasca, Vittorio, Manteca, Alessia, Pichiorri, Floriana, Roseti, Cristina, Torchia, Gregorio, Limatola, Cristina, Grassi, Francesca, Miledi, Ricardo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250127/
https://ncbi.nlm.nih.gov/pubmed/22128328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117975108
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