IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analysis of IRF5 recruitment in macrophages stimulated w...

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Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471814/
https://ncbi.nlm.nih.gov/pubmed/25159141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.034
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