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IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analysis of IRF5 recruitment in macrophages stimulated w...

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Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471814/
https://ncbi.nlm.nih.gov/pubmed/25159141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.034
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