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IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

Interferon Regulatory Factor 5 (IRF5) plays a major role in setting up an inflammatory macrophage phenotype, but the molecular basis of its transcriptional activity is not fully understood. In this study, we conduct a comprehensive genome-wide analysis of IRF5 recruitment in macrophages stimulated w...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471814/
https://ncbi.nlm.nih.gov/pubmed/25159141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.034
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