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Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3
RING E3 ligases catalyze the transfer of ubiquitin (Ub) from E2 ubiquitin-conjugating enzyme thioesterified with Ub (E2~Ub) to substrate. For RING E3 dimers, the RING domain of one subunit and tail of the second cooperate to prime Ub, but how this is accomplished by monomeric RING E3s in the absence...
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| Vydáno v: | Nat Struct Mol Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471106/ https://ncbi.nlm.nih.gov/pubmed/23851457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2621 |
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