Virulence Factors of Pseudomonas aeruginosa Induce Both the Unfolded Protein and Integrated Stress Responses in Airway Epithelial Cells

Pseudomonas aeruginosa infection can be disastrous in chronic lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease. Its toxic effects are largely mediated by secreted virulence factors including pyocyanin, elastase and alkaline protease (AprA). Efficient functioning of the...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: van ‘t Wout, Emily F. A., van Schadewijk, Annemarie, van Boxtel, Ria, Dalton, Lucy E., Clarke, Hanna J., Tommassen, Jan, Marciniak, Stefan J., Hiemstra, Pieter S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471080/
https://ncbi.nlm.nih.gov/pubmed/26083346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004946
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