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RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

Respiratory syncytial virus (RSV) infection can result in severe disease partially due to its ability to interfere with the initiation of Th1 responses targeting the production of type I interferons (IFN) and promoting a Th2 immune environment. Epigenetic modulation of gene transcription has been sh...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Ptaschinski, Catherine, Mukherjee, Sumanta, Moore, Martin L., Albert, Mareike, Helin, Kristian, Kunkel, Steven L., Lukacs, Nicholas W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470918/
https://ncbi.nlm.nih.gov/pubmed/26083387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004978
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