Upregulation of H3K27 Demethylase KDM6 During RSV Infection Enhances Pro-Inflammatory Responses and Immunopathology

Severe disease following RSV infection has been linked to enhanced pro-inflammatory cytokine production that promotes a Th2-type immune environment. Epigenetic regulation in immune cells following viral infection plays a role in the inflammatory response and may result from upregulation of key epige...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Malinczak, Carrie-Anne, Rasky, Andrew J., Fonseca, Wendy, Schaller, Matthew A., Allen, Ronald M., Ptaschinski, Catherine, Morris, Susan, Lukacs, Nicholas W
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6920528/
https://ncbi.nlm.nih.gov/pubmed/31748348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900741
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