Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.

Human melanoma cells required ligation of the integrin alpha v beta 3 to sustain viability and growth in three-dimensional dermal collagen. Variant melanoma cells, lacking the alpha v subunit, progressed rapidly to apoptosis within this matrix, whereas transfection of these cells with an alpha v cDN...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Montgomery, A M, Reisfeld, R A, Cheresh, D A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7522323/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.19.8856
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