Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen.

Human melanoma cells required ligation of the integrin alpha v beta 3 to sustain viability and growth in three-dimensional dermal collagen. Variant melanoma cells, lacking the alpha v subunit, progressed rapidly to apoptosis within this matrix, whereas transfection of these cells with an alpha v cDN...

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Bibliografske podrobnosti
Main Authors: Montgomery, A M, Reisfeld, R A, Cheresh, D A
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC44705/
https://ncbi.nlm.nih.gov/pubmed/7522323
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