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Free energy landscape of activation in a signaling protein at atomic resolution
The interconversion between inactive and active protein states, traditionally described by two static structures, is at the heart of signaling. However, how folded states interconvert is largely unknown due to the inability to experimentally observe transition pathways. Here we explore the free ener...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4470301/ https://ncbi.nlm.nih.gov/pubmed/26073309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8284 |
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