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Evidence against the ‘Y-T coupling’ mechanism of activation in the response regulator NtrC
The dominant theory on the mechanism of response regulators activation in two-component bacterial signaling systems is the ‘Y-T coupling’ mechanism, wherein the χ(1) rotameric state of a highly conserved aromatic residue correlates with the activation of the protein via structural rearrangements cou...
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| Publicado no: | J Mol Biol |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384162/ https://ncbi.nlm.nih.gov/pubmed/24406745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.027 |
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