iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development

Motor neuron diseases (MNDs) are neuromuscular disorders affecting rather exclusively upper motor neurons (UMNs) and/or lower motor neurons (LMNs). The clinical phenotype is characterized by muscular weakness and atrophy leading to paralysis and almost invariably death due to respiratory failure. Ad...

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Detalles Bibliográficos
Publicado en:J Clin Med
Main Authors: Faravelli, Irene, Frattini, Emanuele, Ramirez, Agnese, Stuppia, Giulia, Nizzardo, Monica, Corti, Stefania
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2014
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4470174/
https://ncbi.nlm.nih.gov/pubmed/26237595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm3041124
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