Muc1 is protective during kidney ischemia-reperfusion injury

Ischemia-reperfusion injury (IRI) due to hypotension is a common cause of human acute kidney injury (AKI). Hypoxia-inducible transcription factors (HIFs) orchestrate a protective response in renal endothelial and epithelial cells in AKI models. As human mucin 1 (MUC1) is induced by hypoxia and enhan...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Pastor-Soler, Núria M., Sutton, Timothy A., Mang, Henry E., Kinlough, Carol L., Gendler, Sandra J., Madsen, Cathy S., Bastacky, Sheldon I., Ho, Jacqueline, Al-bataineh, Mohammad M., Hallows, Kenneth R., Singh, Sucha, Monga, Satdarshan P., Kobayashi, Hanako, Haase, Volker H., Hughey, Rebecca P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469889/
https://ncbi.nlm.nih.gov/pubmed/25925251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00066.2015
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