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MUC1 traverses apical recycling endosomes along the biosynthetic pathway in polarized MDCK cells

MUC1 is a heavily glycosylated transmembrane protein localized at the apical surface of polarized epithelial cells. Here, we examined the biosynthetic route of newly synthesized MUC1 in polarized Madin-Darby canine kidney (MDCK) cells. Apically and basolaterally destined cargo are sorted at the tran...

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Autors principals: Mattila, Polly E., Kinlough, Carol L., Bruns, Jennifer R., Weisz, Ora A., Hughey, Rebecca P.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625034/
https://ncbi.nlm.nih.gov/pubmed/19453277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2009.088
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