N-glycosylation is essential for ileal ASBT function and protection against proteases

The bile acid transporter ASBT is a glycoprotein responsible for active absorption of bile acids. Inhibiting ASBT function and bile acid absorption is an attractive approach to lower plasma cholesterol and improve glucose imbalance in diabetic patients. Deglycosylation of ASBT was shown to decrease...

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Bibliografski detalji
Izdano u:Am J Physiol Cell Physiol
Glavni autori: Muthusamy, Saminathan, Malhotra, Pooja, Hosameddin, Mobashir, Dudeja, Amish K., Borthakur, Sujata, Saksena, Seema, Gill, Ravinder K., Dudeja, Pradeep K., Alrefai, Waddah A.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Call for Papers
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469748/
https://ncbi.nlm.nih.gov/pubmed/25855079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00023.2015
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