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N-glycosylation is essential for ileal ASBT function and protection against proteases

The bile acid transporter ASBT is a glycoprotein responsible for active absorption of bile acids. Inhibiting ASBT function and bile acid absorption is an attractive approach to lower plasma cholesterol and improve glucose imbalance in diabetic patients. Deglycosylation of ASBT was shown to decrease...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Am J Physiol Cell Physiol
Main Authors: Muthusamy, Saminathan, Malhotra, Pooja, Hosameddin, Mobashir, Dudeja, Amish K., Borthakur, Sujata, Saksena, Seema, Gill, Ravinder K., Dudeja, Pradeep K., Alrefai, Waddah A.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469748/
https://ncbi.nlm.nih.gov/pubmed/25855079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00023.2015
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