Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS

Hydrophilic interaction-ultra high performance liquid chromatography (HILIC-UHPLC) allows the analysis of highly polar metabolites, providing complementary information to reversed-phase (RP) chromatography. By optimization of the preparation and analytical conditions in HILIC mode, HILIC-UHPLC/MS wa...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Zhao, Longshan, Xiong, Zhili, Lu, Xiumei, Zheng, Shuning, Wang, Fang, Ge, Lin, Su, Guangyue, Yang, Jingyu, Wu, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469692/
https://ncbi.nlm.nih.gov/pubmed/26080063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129146
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