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Study on degradation kinetics of epalrestat in aqueous solutions and characterization of its major degradation products under stress degradation conditions by UHPLC-PDA-MS/MS
Drug stability is closely related to drug safety and needs to be considered in the process of drug production, package and storage. To investigate the stability of epalrestat, a carboxylic acid derivative, a reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed in this...
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| Опубликовано в: : | J Pharm Anal |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Xi'an Jiaotong University
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6931074/ https://ncbi.nlm.nih.gov/pubmed/31890342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2018.08.002 |
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