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Interspecies Pharmacokinetic Modeling of Subcutaneous Absorption of Rituximab in Mice and Rats

PURPOSE: To investigate the effect of dose level and anatomical site of injection on the pharmacokinetics of rituximab in mice, and to evaluate the utility of a pharmacokinetic model for describing interspecies differences in subcutaneous absorption between mice and rats. METHODS: Rituximab serum co...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharm Res
Main Authors: Kagan, Leonid, Zhao, Jie, Mager, Donald E.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469501/
https://ncbi.nlm.nih.gov/pubmed/24852895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1416-1
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