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Population Pharmacodynamic Modeling of Exenatide after Two-week Treatment in STZ/NA Diabetic Rats

The purpose of this study is to investigate the effect of exenatide on glycemic control following two administration routes in a streptozotocin/nicotinamide (STZ/NA)-induced diabetic rat model and to develop a pharmacodynamic model to better understand disease progression and the action of exenatide...

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Hlavní autoři: Chen, Ting, Kagan, Leonid, Mager, Donald E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808969/
https://ncbi.nlm.nih.gov/pubmed/23897494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23682
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