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Interspecies Pharmacokinetic Modeling of Subcutaneous Absorption of Rituximab in Mice and Rats
PURPOSE: To investigate the effect of dose level and anatomical site of injection on the pharmacokinetics of rituximab in mice, and to evaluate the utility of a pharmacokinetic model for describing interspecies differences in subcutaneous absorption between mice and rats. METHODS: Rituximab serum co...
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| Publicado no: | Pharm Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4469501/ https://ncbi.nlm.nih.gov/pubmed/24852895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1416-1 |
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